Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159071 | 0.88 | P2RY1 (0.48) | P2RY1ACACB | |
| SCHEMBL21736840 | 0.86 | PARP10 (0.48) | KCNH2ACACB | |
| SCHEMBL13439696 | 0.85 | SIGMAR1 (0.48) | — | |
| SCHEMBL13439757 | 0.83 | P2RY1 (0.56) | P2RY1KCNH2HRH3 | |
| SCHEMBL14159031 | 0.79 | HRH3 (0.51) | HRH3 | |
| SCHEMBL13439710 | 0.77 | GPR119 (0.58) | — | |
| SCHEMBL27358303 | 0.76 | TLR8 (0.48) | — | |
| SCHEMBL13450959 | 0.75 | P2RY1 (0.49) | P2RY1 | |
| SCHEMBL20374442 | 0.74 | PARP10 (0.45) | KCNH2ACACB | |
| SCHEMBL13439758 | 0.74 | HRH3 (0.49) | P2RY1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |