Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159048 | 0.88 | P2RY1 (0.47) | P2RY1ACACB | |
| SCHEMBL13450959 | 0.87 | P2RY1 (0.49) | P2RY1CYP3A4ACHEMAOBSIGMAR1 | |
| SCHEMBL13462931 | 0.85 | P2RY1 (0.49) | P2RY1CYP3A4ACHEMAOBSIGMAR1 | |
| SCHEMBL13439736 | 0.84 | P2RY1 (0.57) | P2RY1CYP3A4ACHEMAOBSIGMAR1 | |
| SCHEMBL21736840 | 0.84 | PARP10 (0.48) | ACACB | |
| SCHEMBL13439696 | 0.83 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL13439710 | 0.75 | GPR119 (0.58) | — | |
| SCHEMBL20374442 | 0.73 | PARP10 (0.45) | ACACB | |
| SCHEMBL16997126 | 0.72 | TDP1 (0.50) | CYP3A4 | |
| SCHEMBL13439757 | 0.72 | P2RY1 (0.56) | P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |