Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415502 | 0.91 | NR3C1 (0.48) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL1414860 | 0.86 | NR3C1 (0.42) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL838520 | 0.80 | NR3C1 (0.48) | NR3C1CYP11B2CYP11B1PGRHPGD | |
| SCHEMBL837940 | 0.70 | NR3C1 (0.51) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL838181 | 0.70 | NR3C1 (0.47) | NR3C1CYP11B2CYP11B1PGR | |
| SCHEMBL837594 | 0.70 | NR3C1 (0.51) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL4761900 | 0.70 | NR3C1 (0.46) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL4719472 | 0.69 | CYP11B1 (0.60) | NR3C1CYP11B2CYP11B1 | |
| SCHEMBL3659346 | 0.69 | NR3C1 (0.38) | NR3C1CYP11B2CYP11B1PGRHPGD | |
| SCHEMBL4277680 | 0.69 | NR3C1 (0.68) | NR3C1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205562-B1 | 1,1,1-TRIFLUORO-2-HYDROXY-3-PHENYLPROPANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-03-16 | — | — | EP | claimed |