⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552841 | 0.86 | — | — | |
| SCHEMBL304378 | 0.84 | FAAH (0.48) | — | |
| SCHEMBL1415936 | 0.79 | — | — | |
| SCHEMBL6235948 | 0.77 | — | — | |
| SCHEMBL127775 | 0.77 | — | — | |
| SCHEMBL5483012 | 0.76 | — | — | |
| SCHEMBL7319073 | 0.75 | — | — | |
| SCHEMBL127675 | 0.75 | — | — | |
| SCHEMBL28518874 | 0.75 | — | — | |
| SCHEMBL129557 | 0.73 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268825-B2 | Method for the treatment of anthrax infections | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| EP-2165830-B1 | Lithographic printing plate precursor and printing method using the same | FUJIFILM CORP (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20100305119-A1 | Method for the treatment of anthrax infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-12-02 | — | — | US | disclosed |
| US-20100071574-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2165830-A1 | Lithographic printing plate precursor and printing method using the same | Fujifilm Corporation (JP) | 2010-03-24 | — | — | EP | disclosed |
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| EP-0966464-B1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| CN-1091109-C | Substituted 2, 4-diaminopyrimidines | BASLIER PHARMACEUTICALS AG (CH) | 2002-09-18 | — | — | CN | disclosed |
| US-6114330-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| CN-1024669-C | Process for preparing cephem compounds | TIKOSAWA PHARMACEUTICAL CO LTD (JP) | 1994-05-25 | — | — | CN | disclosed |
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0307804-B1 | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| US-4952578-A | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| US-4918074-A | CALCIUM ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| CN-1032540-A | Cephem compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-04-26 | — | — | CN | disclosed |
| EP-0307804-A2 | Cephem compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| EP-0217142-A2 | A polyazaheterocyclic compound | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-08 | — | — | EP | disclosed |