Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601757 | 0.92 | ACKR3 (0.40) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL3590131 | 0.91 | KMT2A (0.46) | ALDH1A1KMT2AMEN1BCHEACHE | |
| SCHEMBL3600013 | 0.91 | SIGMAR1 (0.44) | ALDH1A1MAPTPKMBCHEACHE | |
| SCHEMBL3590840 | 0.91 | ACHE (0.40) | MAPTPKMBCHEACHEALOX5 | |
| SCHEMBL3604419 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTPKMBCHEACHE | |
| SCHEMBL3596607 | 0.88 | SIGMAR1 (0.41) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL3603360 | 0.88 | HTR2A (0.48) | BCHEACHEALOX5MAOASIGMAR1 | |
| SCHEMBL3586986 | 0.87 | KDM4E (0.43) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL3589358 | 0.87 | MEN1 (0.42) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL3598642 | 0.87 | SIGMAR1 (0.48) | MAPTPKMBCHEACHEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |