Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12747952 | 0.79 | ALDH1A1 (1.00) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16566586 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23959777 | 0.78 | CYP1A2 (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4512999 | 0.78 | CYP1A2 (1.00) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4512996 | 0.78 | CYP1A2 (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL341142 | 0.77 | SLC40A1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8956204 | 0.76 | KMT2A (0.77) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL1695444 | 0.76 | KDR (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31206215 | 0.76 | KMT2A (0.77) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL29851236 | 0.76 | KDR (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074068-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS ANTIAMYLOIDOGENEIC AGENTS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2008-06-26 | — | — | WO | disclosed |