Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695444 | 1.00 | KDR (0.71) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10994584 | 0.85 | KDR (0.58) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29903003 | 0.85 | HSP90AA1 (0.57) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1753903 | 0.84 | TDP1 (0.79) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL14851783 | 0.84 | TDP1 (0.69) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL27599095 | 0.84 | TDP1 (0.67) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3909349 | 0.84 | TDP1 (0.67) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3549883 | 0.84 | CYP1A2 (0.71) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29918706 | 0.84 | TDP1 (0.71) | KDRMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5053488 | 0.84 | TDP1 (0.71) | KDRMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914256-B1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES INC (US) | 2024-05-29 | — | — | EP | disclosed |
| US-11773101-B2 | GPR35 modulators | PROMETHEUS BIOSCIENCES, INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773101-B2 | GPR35 modulators | GPR35, GPR55, GPR65 | KDR 1382/4885MEN1 3744/4885KMT2A 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.