SCHEMBL1416628

SCHEMBL1416628

CCCCCCCCCCCCCC(CN(CC=O)C(=O)O)NC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.37
FFAR1 O14842 2/20 0.37
MAPT P10636 1/20 0.36
LCK P06239 1/20 0.36
PPARD Q03181 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
PLA2G2C Q5R387 1/20 0.35
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35
ADH7 P40394 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
ACE2 Q9BYF1 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.33
PLA2G10 O15496 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416599 1.00 GPR84 (0.37) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1416570 1.00 GPR84 (0.37) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1416578 1.00 GPR84 (0.37) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1416474 1.00 GPR84 (0.37) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1416905 1.00 GPR84 (0.37) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1416636 0.99 GPR84 (0.34) GPR84FFAR1MAPTLCKPPARD
SCHEMBL4238288 0.94 PLA2G2C (0.34) PLA2G2C
SCHEMBL1416564 0.91 FAAH (0.41) FFAR1MAPTPPARDFFAR4
SCHEMBL1416478 0.90 ALDH1A1 (0.44) FFAR1MAPTPPARDFFAR4
SCHEMBL1416767 0.86 PPARG (0.43) FFAR1MAPTPPARDFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879856-B1 ALKYL-, ALKENYL- AND ALKYNYL CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF SANOFI AVENTIS (FR) 2011-03-16 EP claimed
US-20090088470-A1 ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS SANOFI-AVENTIS (FR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088470-A1 ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS ALK, ALKBH3, IDH1 GPR84 1280/4885FFAR1 468/4885MAPT 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.