Dihydroxyacetone

Dihydroxyacetone

SCHEMBL14166391

CCOCC.O=C(CO)CO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SOAT1 P35610 1/20 0.35
THRB P10828 1/20 0.34
TRPA1 O75762 1/20 0.32
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL28028782 0.83
SCHEMBL9510648 0.82
Ether SCHEMBL251857 0.81 FFAR3 (0.44) ALDH1A1TSHRLMNAHSD17B10ALOX15
Dihydroxyacetone SCHEMBL28214102 0.79
Ether SCHEMBL9560131 0.79 ALOX15 (0.46) ALDH1A1TSHRTDP1LMNAHSD17B10
Ether SCHEMBL15110284 0.79 ALOX15 (0.46) ALDH1A1TSHRTDP1LMNAHSD17B10
Ether SCHEMBL8362190 0.79 FFAR3 (0.42) ALDH1A1TSHRLMNAHSD17B10ALOX15
Ether SCHEMBL5207262 0.78 ALDH1A1 (0.48) ALDH1A1TSHRTDP1LMNAHSD17B10
Ether SCHEMBL4686512 0.78 ALDH1A1 (0.48) ALDH1A1TSHRTDP1LMNAHSD17B10
Ether SCHEMBL347668 0.78 TDP1 (0.67) ALDH1A1TSHRTDP1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012168126-A2 PROCESS FOR PRODUCING A TRANSPARENT COSMETIC CLEANSING COMPOSITION HENKEL AG & CO. KGAA (DE) 2012-12-13 WO disclosed