Ether

Ether

SCHEMBL9560131

CCOCC.NC(=O)CO.NC(=O)CO

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.46
ALDH1A1 P00352 6/20 0.41
TSHR P16473 2/20 0.39
LMNA P02545 3/20 0.35
HSD17B10 Q99714 2/20 0.35
BLM P54132 2/20 0.33
PMP22 Q01453 2/20 0.33
CYP1A2 P05177 2/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
THRB P10828 1/20 0.33
SOAT1 P35610 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL15110284 1.00 ALOX15 (0.46) ALOX15ALDH1A1TSHRLMNAHSD17B10
Propionamide SCHEMBL28035985 0.85 ALOX15 (0.48) ALOX15ALDH1A1TSHRLMNAHSD17B10
Ether SCHEMBL1011439 0.84
Ether SCHEMBL28156440 0.82 ALOX15 (0.46) ALOX15ALDH1A1TSHRLMNAHSD17B10
Ether SCHEMBL4328551 0.82 ALOX15 (0.46) ALOX15ALDH1A1TSHRLMNAHSD17B10
Ether SCHEMBL442290 0.81
Ether SCHEMBL173703 0.81
Ether SCHEMBL28028782 0.80
Ether SCHEMBL2555391 0.80 ALOX15 (0.43) ALOX15ALDH1A1TSHRLMNAHSD17B10
Ether SCHEMBL2549388 0.80 ALDH1A1 (0.46) ALOX15ALDH1A1TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553116-A1 PORPHYRIN DERIVATIVES QUEEN'S UNIVERSITY AT KINGSTON (CA) 1993-08-04 EP claimed
WO-1992006097-A1 PORPHYRIN DERIVATIVES QUEEN'S UNIVERSITY AT KINGSTON (CA) 1992-04-16 WO claimed