Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | APAF1 | O14727 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 15/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416679 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416588 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416565 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416692 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL28567948 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416563 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL5961696 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416736 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416690 | 1.00 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL1416512 | 0.97 | MAPK1 (0.64) | MAPK1MEN1HSP90AA1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425268-B2 | ORGANIC SULFATES AS IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2011-03-16 | — | — | EP | claimed |
| US-7544807-B2 | Alkyl sulfates such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers; low melting | MERCK PATENT GMBH (DE) | 2009-06-09 | — | — | US | claimed |
| EP-1425268-B1 | ORGANIC SULFATES AS IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2008-02-27 | — | — | EP | claimed |
| US-20080033178-A1 | Alkyl sulfates such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers; low melting | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | claimed |
| US-7252791-B2 | sulfonic acids and salts such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers | MERCK PATENT GMBH (DE) | 2007-08-07 | — | — | US | claimed |
| WO-2006111712-A2 | IONIC LIQUIDS AND USES THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2006-10-26 | — | — | WO | claimed |
| EP-1425268-B2 | ORGANIC SULFATES AS IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2011-03-16 | — | — | EP | disclosed |
| US-7544807-B2 | Alkyl sulfates such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers; low melting | MERCK PATENT GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| EP-1425268-B1 | ORGANIC SULFATES AS IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20080033178-A1 | Alkyl sulfates such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers; low melting | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-7252791-B2 | sulfonic acids and salts such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers | MERCK PATENT GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-20040262578-A1 | sulfonic acids and salts such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers | MERCK PATENT GMBH (DE) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040262578-A1 | sulfonic acids and salts such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers | RPS4Y1, HSPA4, RPS4X | MAPK1 303/4885MEN1 4370/4885HSP90AA1 81/4885 |
| US-20080033178-A1 | Alkyl sulfates such as 1-ethyl-3-methylimidazolium butyl sulfate, used as solvents or solvent adjuvants in chemical reactions, extraction agents or heat carriers in heat exchangers; low melting | MRPS34, HSPA4, SLC43A1 | MAPK1 423/4885MEN1 4582/4885HSP90AA1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.