Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247980 | 0.80 | KDM4E (0.31) | — | |
| SCHEMBL8570761 | 0.80 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL15794176 | 0.79 | PHF8 (0.32) | — | |
| SCHEMBL13644766 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL22021683 | 0.74 | NAMPT (0.32) | — | |
| SCHEMBL21341604 | 0.74 | LMNA (0.34) | ALDH1A1 | |
| SCHEMBL17615113 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL18018692 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL13407585 | 0.73 | CHRNB2 (0.31) | — | |
| SCHEMBL28057793 | 0.73 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718266-A1 | PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168350-A1 | PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-13 | — | — | WO | disclosed |