SCHEMBL1416092

SCHEMBL1416092

CCOCCNC(=O)OCCOc1[c]cccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 1/20 0.39
ACHE P22303 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
ASAH1 Q13510 1/20 0.37
HPGD P15428 2/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416259 0.88 SMN1; SMN2 (0.47) SMN1; SMN2LMNAL3MBTL1MAPTACHE
SCHEMBL1416212 0.87 HPGD (0.42) SMN1; SMN2LMNAL3MBTL1MAPTHPGD
SCHEMBL1416274 0.86 SMN1; SMN2 (0.46) SMN1; SMN2LMNAL3MBTL1MAPTACHE
SCHEMBL1416764 0.84 SMN1; SMN2 (0.41) SMN1; SMN2LMNAL3MBTL1ASAH1HPGD
SCHEMBL1415807 0.84 SMN1; SMN2 (0.38) SMN1; SMN2LMNAL3MBTL1MAPTACHE
SCHEMBL1416012 0.82 SMN1; SMN2 (0.43) SMN1; SMN2LMNAASAH1HPGDHTT
SCHEMBL2449865 0.79 L3MBTL1 (0.38) SMN1; SMN2LMNAL3MBTL1MAPTKMT2A
SCHEMBL1416094 0.78 L3MBTL1 (0.44) SMN1; SMN2LMNAL3MBTL1MAPTACHE
SCHEMBL29068363 0.75 CA12 (0.50) L3MBTL1
SCHEMBL9324825 0.75 ALDH1A1 (0.41) SMN1; SMN2LMNAL3MBTL1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed