Cetiedil

Cetiedil

SCHEMBL14169136

O=C(OCCN1CCCCCC1)[C@@H](c1ccsc1)C1CCCCC1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
TSHR P16473 2/20 0.44
CHRM2 P08172 2/20 0.44
HTR1A P08908 2/20 0.44
ADRA2A P08913 2/20 0.44
CHRM1 P11229 2/20 0.44
DRD1 P21728 2/20 0.44
DRD3 P35462 2/20 0.44
SLC6A3 Q01959 2/20 0.44
SLC6A2 P23975 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
KCNH2 Q12809 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HRH3 Q9Y5N1 2/20 0.43
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetiedil SCHEMBL458084 1.00 CYP3A4 (0.44) CYP3A4CYP1A2CYP2D6TSHRCHRM2
Cetiedil SCHEMBL5149883 0.90 C3AR1 (0.42) CYP3A4CYP1A2CYP2D6TSHRCHRM2
Cetiedil SCHEMBL121380 0.89 CYP3A4 (0.40) CYP3A4CYP1A2CYP2D6TSHRCHRM2
SCHEMBL11366829 0.81 SLC6A3 (0.48) CYP3A4CYP1A2CYP2D6TSHRCHRM2
SCHEMBL14862650 0.80 SLC6A3 (0.46) CYP3A4CYP1A2CYP2D6TSHRCHRM2
SCHEMBL17111285 0.79 KMT2A (0.49) CYP3A4CYP1A2CYP2D6TSHRCHRM2
SCHEMBL11368109 0.78 SLC6A3 (0.58) CYP3A4CYP1A2CYP2D6TSHRCHRM2
SCHEMBL8975472 0.78 TP53 (0.72) CYP3A4CYP1A2CYP2D6TSHRSLC6A3
Cinepazide SCHEMBL28086342 0.76 KDM4E (0.47) CYP3A4TP53TDP1KMT2ABCHE
SCHEMBL6191571 0.76 SLC6A3 (0.40) CYP3A4CYP1A2CYP2D6TSHRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7385064-B1 Catalysts for use in enantioselective synthesis THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2008-06-10 US disclosed
US-7385064-B1 Catalysts for use in enantioselective synthesis THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2008-06-10 US disclosed