SCHEMBL141701

SCHEMBL141701

CCCCOCCOc1ccc(-c2cc(F)c(C#N)c(F)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.58
RARA P10276 1/20 0.58
TSHR P16473 1/20 0.46
MAPT P10636 2/20 0.45
CYP3A4 P08684 4/20 0.44
CYP2D6 P10635 4/20 0.44
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 1/20 0.42
HRH2 P25021 3/20 0.41
HRH1 P35367 3/20 0.41
HRH3 Q9Y5N1 3/20 0.41
CYP19A1 P11511 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP1A2 P05177 2/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618076 0.92 KDM4E (0.51) RARBRARATSHRMAPTCYP3A4
SCHEMBL14480433 0.90 KDM4E (0.53) RARBRARATSHRMAPTCYP3A4
SCHEMBL14480467 0.90 RARA (0.45) RARBRARAMAPTCYP3A4CYP2D6
SCHEMBL141714 0.88 RARB (0.44) RARBRARAKDM4EHRH2HRH1
SCHEMBL12477887 0.87 RARB (0.47) RARBRARATSHRKDM4EALDH1A1
SCHEMBL14964550 0.85 RARB (0.45) RARBRARATSHRMAPTCYP3A4
SCHEMBL142121 0.83 RARB (0.44) RARBRARATSHRMAPTCYP3A4
SCHEMBL14964552 0.83 RARB (0.44) RARBRARATSHRMAPTKDM4E
SCHEMBL9506551 0.83 KDM4E (0.50) RARBRARAMAPTCYP3A4CYP2D6
SCHEMBL11121389 0.83 RARB (0.60) RARBRARATSHRMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130341574-A1 PHOTOREFRACTIVE COMPOSITION AND DEVICE COMPRISING THE COMPOSITION NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
US-20130341573-A1 PHOTOREFRACTIVE COMPOSITION COMPRISING ELECTROLYTES IN A PHOTOREFRACTIVE LAYER AND METHOD OF MAKING THEREOF NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
US-20130170016-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-07-04 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
US-20130128339-A1 PHOTOREFRACTIVE COMPOSITION RESPONSIVE TO MULTIPLE LASER WAVELENGTHS ACROSS THE VISIBLE LIGHT SPECTRUM NITTO DENKO CORPORATION (JP) 2013-05-23 US disclosed
WO-2012116105-A1 A PHOTOREFRACTIVE COMPOSITION AND DEVICE COMPRISING THE COMPOSITION NITTO DENKO CORPORATION (JP) 2012-08-30 WO disclosed
US-20120058418-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
US-20120058418-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
WO-2010141323-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-12-09 WO disclosed