SCHEMBL14480467

SCHEMBL14480467

CCCOc1ccc(-c2cc(F)c(C#N)c(F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARA P10276 1/20 0.45
RARB P10826 1/20 0.45
KDM4E B2RXH2 6/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
HPGD P15428 4/20 0.42
HSD17B10 Q99714 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ERN1 O75460 1/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAOB P27338 1/20 0.41
MMP2 P08253 2/20 0.41
ACACB O00763 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618076 0.93 KDM4E (0.51) RARARARBKDM4EALDH1A1MAPT
SCHEMBL14480433 0.91 KDM4E (0.53) RARARARBKDM4EALDH1A1MAPT
SCHEMBL141701 0.90 RARB (0.58) RARARARBKDM4EALDH1A1MAPT
SCHEMBL24076492 0.89 CYP11B1 (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL9507851 0.88 KDM4E (0.45) RARARARBKDM4EALDH1A1MAPT
SCHEMBL141714 0.85 RARB (0.44) RARARARBKDM4ESMN1; SMN2MMP2
SCHEMBL9506551 0.84 KDM4E (0.50) RARARARBKDM4EALDH1A1MAPT
SCHEMBL25707182 0.83 TRPV4 (0.45) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL9506414 0.82 KDM4E (0.50) RARARARBKDM4EALDH1A1MAPT
SCHEMBL30933437 0.81 ALDH1A1 (0.40) RARARARBKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371485-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device Semiconductor Energy Laboraory Co., LTD. (JP) 2016-06-21 US disclosed
US-9371485-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device Semiconductor Energy Laboraory Co., LTD. (JP) 2016-06-21 US disclosed
US-9371485-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device Semiconductor Energy Laboraory Co., LTD. (JP) 2016-06-21 US disclosed
US-20150210924-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-07-30 US disclosed
US-20150210924-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-07-30 US disclosed
US-20150210924-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2015-07-30 US disclosed
US-9039931-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-05-26 US disclosed
US-9039931-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-05-26 US disclosed
US-9039931-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-05-26 US disclosed
US-20140117285-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-01 US disclosed
WO-2013012020-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 WO disclosed
WO-2013012020-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 WO disclosed
US-20130020023-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020023-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020023-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-24 US disclosed
WO-2013008657-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-17 WO disclosed
WO-2013008657-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-17 WO disclosed
US-20130009094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-10 US disclosed
US-20130009094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-10 US disclosed
US-20130009094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-10 US disclosed