Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.76 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.58 |
| ▸ | IKBKB | O14920 | 3/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14169345 | 0.90 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL4736185 | 0.83 | PIK3CG (0.80) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL4733859 | 0.83 | PIK3CG (0.80) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL10977837 | 0.82 | PIK3CG (0.78) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL4733655 | 0.81 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL7464195 | 0.78 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL14163090 | 0.78 | CDK2 (0.56) | CDK5CDK5R1IKBKBSYKABL1 | |
| SCHEMBL27116598 | 0.78 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBCDK5MEN1 | |
| SCHEMBL14172776 | 0.77 | PLK1 (0.72) | PIK3CGNPC1RAB9ASYKABL1 | |
| SCHEMBL4380820 | 0.76 | PIK3CG (0.75) | PIK3CGPIK3CAPIK3CBCDK5IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153822-A1 | Methods of treating pain | INGENIUM PHARMACEUTICALS GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153822-A1 | Methods of treating pain | OPRL1, ACHE, OPRK1 | PIK3CG 4311/4885PIK3CA 4390/4885PIK3CB 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.