SCHEMBL14173524

SCHEMBL14173524

O=C(O)c1cc(N=S)ccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.72
▸ MEN1 O00255 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ ALPL P05186 1/20 0.60
▸ ALPI P09923 1/20 0.60
▸ ALPG P10696 1/20 0.60
▸ ATM Q13315 1/20 0.58
▸ PLEC Q15149 1/20 0.58
▸ CA9 Q16790 16/20 0.58
▸ CA1 P00915 14/20 0.58
▸ CA2 P00918 14/20 0.58
▸ CA12 O43570 6/20 0.56
▸ DNASE1L3 Q13609 1/20 0.54
▸ PRMT1 Q99873 1/20 0.54
▸ CA14 Q9ULX7 2/20 0.53
▸ CA7 P43166 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12997225 0.89 USP2 (0.72) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL2755000 0.89 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL15369507 0.87 USP2 (0.66) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL15369505 0.87 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL15304973 0.87 USP2 (0.71) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.84 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.84 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14013402 0.84 USP2 (0.64) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL19928054 0.84 USP2 (0.64) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL10098714 0.84 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656410-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2017-07-05 — — EP disclosed
US-20150212068-A1 Cholyl-L-Lysyl-Fluorescein Assay NOVASSAY SA (CH) 2015-07-30 — — US disclosed
US-20130296288-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-11-07 — — US disclosed
US-20080139493-A1 Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers UCL BUSINESS PLC (GB) 2008-06-12 — — US disclosed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 — — US disclosed
US-7183405-B2 Compositions and methods for labeling oligonucleotides SYN GEN, INC. (US) 2007-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139493-A1 Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers CBR3, CBR1, KCNQ3 USP2 3328/4885L3MBTL1 2053/4885MEN1 1701/4885
US-20130296288-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC26A3, SLCO4C1, ICMT USP2 4747/4885L3MBTL1 3388/4885MEN1 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback