Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174738 | 0.86 | TP53 (0.65) | OPRM1TP53SMN1; SMN2MLYCDCNR2 | |
| SCHEMBL3146589 | 0.86 | PHLPP2 (0.44) | OPRM1TP53SMN1; SMN2MLYCDSIGMAR1 | |
| SCHEMBL14174742 | 0.86 | TP53 (0.42) | OPRM1TP53SMN1; SMN2MLYCDCNR2 | |
| SCHEMBL7826288 | 0.84 | MLYCD (0.43) | OPRM1TP53SMN1; SMN2MLYCDCNR2 | |
| SCHEMBL7830726 | 0.84 | MEN1 (0.45) | TP53SMN1; SMN2MLYCDROCK2 | |
| SCHEMBL14174753 | 0.83 | TP53 (0.53) | TP53SMN1; SMN2MLYCD | |
| SCHEMBL14174750 | 0.82 | TP53 (0.47) | OPRM1TP53SMN1; SMN2MLYCDCNR2 | |
| SCHEMBL7830722 | 0.82 | MLYCD (0.41) | TP53SMN1; SMN2MLYCDROCK2 | |
| SCHEMBL14174754 | 0.81 | KDM4E (0.48) | TP53SMN1; SMN2MLYCDROCK2 | |
| SCHEMBL14174746 | 0.81 | MLYCD (0.42) | OPRM1TP53SMN1; SMN2MLYCDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384952-B2 | Pyrazolopyrimidine compound and a process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1857459-A2 | Pyrazolopyrimidine compound and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |