Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174752 | 0.84 | OPRM1 (0.49) | MLYCDTP53SMN1; SMN2ROCK2CNR2 | |
| SCHEMBL7830722 | 0.84 | MLYCD (0.41) | MLYCDTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL14174742 | 0.84 | TP53 (0.42) | MLYCDTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL7828136 | 0.84 | TSHR (0.44) | MLYCDTP53SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7830726 | 0.82 | MEN1 (0.45) | MLYCDTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL14174738 | 0.81 | TP53 (0.65) | MLYCDTP53SMN1; SMN2CNR2OPRM1 | |
| SCHEMBL14174746 | 0.80 | MLYCD (0.42) | MLYCDTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL14174754 | 0.80 | KDM4E (0.48) | MLYCDTP53SMN1; SMN2ROCK2ALDH1A1 | |
| SCHEMBL14174753 | 0.79 | TP53 (0.53) | MLYCDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL7825103 | 0.78 | ALDH1A1 (0.46) | TP53SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |