Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826288 | 0.84 | MLYCD (0.43) | MLYCDROCK2ALDH1A1TSHRTP53 | |
| SCHEMBL7830726 | 0.84 | MEN1 (0.45) | MLYCDRAB9AROCK2ALDH1A1TSHR | |
| SCHEMBL14174752 | 0.82 | OPRM1 (0.49) | MLYCDROCK2TP53SMN1; SMN2 | |
| SCHEMBL14174742 | 0.82 | TP53 (0.42) | MLYCDROCK2ALDH1A1TSHRTP53 | |
| SCHEMBL7831239 | 0.81 | TSHR (0.46) | RAB9AALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL14174739 | 0.79 | MLYCD (0.63) | MLYCDALDH1A1UTS2R | |
| SCHEMBL14174740 | 0.79 | SMN1; SMN2 (0.62) | MLYCDROCK2ALDH1A1TSHRTP53 | |
| SCHEMBL14174738 | 0.79 | TP53 (0.65) | MLYCDRAB9ATP53SMN1; SMN2 | |
| SCHEMBL14174743 | 0.78 | STAT3 (0.40) | MLYCDRAB9AROCK2ALDH1A1TP53 | |
| SCHEMBL14174741 | 0.78 | CYP3A4 (0.44) | MLYCDROCK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |