Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176080 | 0.87 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL12677238 | 0.87 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL17619493 | 0.84 | ALDH1A1 (0.71) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL12677409 | 0.84 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL14176067 | 0.83 | LMNA (0.65) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL14176070 | 0.82 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL14176066 | 0.82 | MAP4K4 (0.48) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL19659932 | 0.82 | KDM4E (0.60) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL19652416 | 0.80 | PTGS2 (0.76) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL14176079 | 0.80 | ALDH1A1 (0.57) | MEN1KMT2ASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932833-A1 | NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |