Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626939 | 0.83 | CYP2C19 (0.36) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL8468255 | 0.80 | CYP2C19 (0.34) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL1417675 | 0.79 | CYP4F2 (0.37) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL4811675 | 0.79 | MAPT (0.41) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL29168788 | 0.79 | SIRT2 (0.40) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL31369191 | 0.79 | CYP4F2 (0.36) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL4349604 | 0.78 | CYP2C19 (0.34) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL29328600 | 0.78 | CYP4F2 (0.38) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR | |
| SCHEMBL28553004 | 0.78 | SIRT2 (0.43) | CYP2C19CYP4F2CYP4A11CYP3A4 | |
| SCHEMBL2648433 | 0.78 | CYP2C19 (0.36) | CYP2C19CYP4F2CYP4A11CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918028-B | N-[(mixing) arylalkyl] pyrazoles (sulfo-) carboxylic acid amides and the assorted analogue replaced thereof | BAYER CROPSCIENCE AG (DE) | 2016-04-27 | — | — | CN | disclosed |
| US-8999956-B2 | N-[(het)arylalkyl)] pyrazole(thio)carboxamides and their heterosubstituted analogues | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| EP-2576517-B1 | N-[(HET)ARYLALKYL)]PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER IP GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| EP-2576517-A1 | N-[(HET)ARYLALKYL)]PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | Bayer Cropscience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20130079302-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE(THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-28 | — | — | US | disclosed |
| CN-102918028-A | N-[(het)arylalkyl)] pyrazole (thio)carboxamides and their heterosubstituted analogues | BAYER CROPSCIENCE AG | 2013-02-06 | — | — | CN | disclosed |
| WO-2011151370-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079302-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE(THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | HDHD5, CYP51A1, NOD1 | CYP2C19 39/4885CYP4F2 76/4885CYP4A11 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.