Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14177860 | 0.93 | KDM4E (0.47) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL14177862 | 0.84 | KDM4E (0.50) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL14387377 | 0.78 | KMT2A (0.58) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL11930743 | 0.74 | POLB (0.62) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL8067660 | 0.72 | POLB (0.62) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL11026357 | 0.70 | POLB (0.65) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL9885777 | 0.70 | KDM4E (0.60) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL13543489 | 0.70 | MAPT (0.73) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL11710034 | 0.68 | MAPT (0.56) | KDM4EHTTPOLBHSD17B10KMT2A | |
| SCHEMBL9436712 | 0.68 | GSTO1 (0.66) | KDM4EPOLBHSD17B10KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071421-A1 | NITRATE ESTERS OF CARBONIC ANHYDRASE INHIBITORS | NICOX S.A. (FR) | 2008-06-19 | — | — | WO | disclosed |