Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543489 | 0.87 | MAPT (0.73) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL9436722 | 0.85 | POLB (0.58) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL11595503 | 0.83 | POLB (0.56) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL9436712 | 0.82 | GSTO1 (0.66) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13543285 | 0.78 | GSTO1 (0.62) | MAPTPOLBL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL11596502 | 0.77 | AKR1C3 (0.62) | POLBL3MBTL1TDP1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL11719099 | 0.77 | MAPT (0.47) | MAPTPOLBKMT2AHSD17B10KDM4E | |
| SCHEMBL11026357 | 0.75 | POLB (0.65) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL14387377 | 0.75 | KMT2A (0.58) | MAPTPOLBL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL11597366 | 0.75 | GSTO1 (0.50) | POLBL3MBTL1TDP1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029787-A | Basically substituted 3-sulfamoylbenzoic acid derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |