Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14170736 | 0.83 | SRC (0.34) | SRCCASP1CASP8 | |
| SCHEMBL14170755 | 0.82 | SRC (0.38) | SRCCASP1CASP8 | |
| SCHEMBL14170730 | 0.82 | KDM4E (0.36) | SRCCASP1CASP8 | |
| SCHEMBL10332041 | 0.81 | CASP1 (0.40) | SRCCASP1CASP8 | |
| SCHEMBL14170738 | 0.79 | PIK3CD (0.33) | SRCCASP1CASP8 | |
| SCHEMBL14170735 | 0.79 | PIK3CD (0.45) | SRCCASP1CASP8 | |
| SCHEMBL14170781 | 0.79 | SRC (0.33) | SRCCASP1CASP8 | |
| SCHEMBL14170742 | 0.79 | SRC (0.34) | SRCCASP1CASP8 | |
| SCHEMBL14170758 | 0.78 | MMP1 (0.39) | SRCCASP1CASP8 | |
| SCHEMBL14170737 | 0.77 | INMT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390801-B2 | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds | ATHENA NEUROSCIENCES, INC. (US) | 2008-06-24 | — | — | US | disclosed |