Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180786 | 0.99 | CNR1 (0.50) | CNR1SIGMAR1MCHR1NPC1RAB9A | |
| SCHEMBL14180785 | 0.99 | CNR1 (0.50) | CNR1SIGMAR1MCHR1NPC1RAB9A | |
| SCHEMBL4798482 | 0.91 | ALDH1A1 (0.49) | CNR1SIGMAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL4798404 | 0.84 | CNR1 (0.54) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14180888 | 0.83 | CNR1 (0.58) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14180794 | 0.82 | CNR1 (0.53) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4798284 | 0.82 | CNR1 (0.51) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14180976 | 0.82 | CNR1 (0.52) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4800125 | 0.81 | CNR1 (0.70) | CNR1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14180765 | 0.81 | CNR1 (0.56) | CNR1NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |