Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.56 |
| ▸ | ITK | Q08881 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182759 | 1.00 | MAOA (0.56) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182757 | 1.00 | MAOA (0.56) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182905 | 0.95 | MEN1 (0.54) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182768 | 0.92 | KCNQ2 (0.55) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182729 | 0.92 | KCNQ2 (0.55) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182765 | 0.88 | KCNQ2 (0.53) | MAOAMAOBMEN1KMT2AKCNQ2 | |
| SCHEMBL14182699 | 0.88 | MAOA (0.56) | MAOAMAOBMEN1KMT2AITK | |
| SCHEMBL14182774 | 0.88 | MAOA (0.56) | MAOAMAOBMEN1KMT2AITK | |
| SCHEMBL14182743 | 0.88 | KCNK3 (0.61) | MAOAMAOBKMT2AITKKDM4E | |
| SCHEMBL14182732 | 0.88 | KCNK3 (0.61) | MAOAMAOBKMT2AITKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |