Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182726 | 0.89 | ROCK2 (0.44) | MAPTRAB9ANPC1ABCB1MEN1 | |
| SCHEMBL14182776 | 0.89 | PTPN1 (0.46) | MAPTRAB9ANPC1ABCB1MEN1 | |
| SCHEMBL14182735 | 0.89 | MAOA (0.52) | KCNQ2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14182724 | 0.89 | MAOA (0.52) | KCNQ2MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14182705 | 0.88 | MAOA (0.56) | KCNQ2MAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL14182759 | 0.88 | MAOA (0.56) | KCNQ2MAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL14182757 | 0.88 | MAOA (0.56) | KCNQ2MAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL14182719 | 0.88 | MAOA (0.52) | KCNQ2MAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL14182720 | 0.88 | NAMPT (0.44) | KCNQ2MAPTSMN1; SMN2ITKKMT2A | |
| SCHEMBL14182745 | 0.88 | NAMPT (0.44) | KCNQ2MAPTSMN1; SMN2ITKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |