Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182768 | 1.00 | KCNQ2 (0.55) | KCNQ2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL14182862 | 0.95 | PLAU (0.52) | KCNQ2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL14182759 | 0.92 | MAOA (0.56) | KCNQ2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL14182705 | 0.92 | MAOA (0.56) | KCNQ2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL14182757 | 0.92 | MAOA (0.56) | KCNQ2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL14182725 | 0.89 | MAOA (0.47) | MAPTRAB9ANPC1ABCB1MEN1 | |
| SCHEMBL14182737 | 0.89 | MAOA (0.54) | MAPTRAB9ANPC1ITKMEN1 | |
| SCHEMBL14182716 | 0.89 | MAOA (0.54) | MAPTRAB9ANPC1ITKMEN1 | |
| SCHEMBL14182718 | 0.87 | MAOA (0.57) | KCNQ2RAB9ANPC1ITKMEN1 | |
| SCHEMBL14182712 | 0.87 | ALDH1A1 (0.47) | MAPTALDH1A1TP53ITKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |