Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182670 | 0.91 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL14182742 | 0.90 | MAOA (0.51) | ALDH1A1PTPN1NPC1RAB9AENPP3 | |
| SCHEMBL14182667 | 0.90 | MAOA (0.51) | ALDH1A1PTPN1NPC1RAB9AENPP3 | |
| SCHEMBL14182642 | 0.89 | GRM2 (0.52) | ALDH1A1NPC1RAB9AENPP3CA12 | |
| SCHEMBL14182666 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ACA12CA9 | |
| SCHEMBL14182744 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ACA12CA9 | |
| SCHEMBL14182753 | 0.88 | KCNQ2 (0.54) | ALDH1A1NPC1RAB9ATP53ALOX5 | |
| SCHEMBL14182721 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL14182655 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ATP53MAPT | |
| SCHEMBL14182813 | 0.83 | CNR2 (0.44) | ALDH1A1CA12CA9TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |