Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182667 | 1.00 | MAOA (0.51) | MAOAMAOBALDH1A1KDM4ETP53 | |
| SCHEMBL14182642 | 0.91 | GRM2 (0.52) | ALDH1A1KDM4ETP53HPGDNPC1 | |
| SCHEMBL14182666 | 0.90 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1KDM4ETP53 | |
| SCHEMBL14182670 | 0.90 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1KDM4ETP53 | |
| SCHEMBL14182772 | 0.90 | ALDH1A1 (0.49) | MAOBALDH1A1KDM4ETP53HPGD | |
| SCHEMBL14182744 | 0.90 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1KDM4ETP53 | |
| SCHEMBL14182721 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4ETP53HPGDNPC1 | |
| SCHEMBL14182655 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4ETP53HPGDNPC1 | |
| SCHEMBL14182753 | 0.88 | KCNQ2 (0.54) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL14182635 | 0.87 | RAB9A (0.52) | ALDH1A1KDM4ETP53HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |