Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182645 | 0.93 | RAB9A (0.52) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182635 | 0.93 | RAB9A (0.52) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182802 | 0.89 | ALDH1A1 (0.46) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182796 | 0.88 | RAB9A (0.44) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14183003 | 0.87 | ALDH1A1 (0.53) | RAB9AKDM4EALDH1A1TP53HPGD | |
| SCHEMBL14183004 | 0.86 | GRM4 (0.53) | RAB9AKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL14182993 | 0.86 | RAB9A (0.45) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182778 | 0.86 | RAB9A (0.45) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182921 | 0.84 | CNR2 (0.45) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182800 | 0.82 | RAB9A (0.38) | RAB9AKDM4EMAPTAGTR1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |