Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182796 | 0.94 | RAB9A (0.44) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182805 | 0.85 | ALDH1A1 (0.42) | RAB9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14213363 | 0.83 | GRM4 (0.37) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182778 | 0.83 | RAB9A (0.45) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14183000 | 0.82 | RAB9A (0.52) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182793 | 0.82 | ITK (0.44) | RAB9AKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL14182802 | 0.82 | ALDH1A1 (0.46) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL14182794 | 0.80 | KDR (0.46) | RAB9AKDM4EKDRGRM4SMN1; SMN2 | |
| SCHEMBL14182809 | 0.79 | CNR1 (0.36) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL14182801 | 0.79 | ALDH1A1 (0.46) | RAB9AKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |