Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016948 | 0.81 | TGFBR1 (0.40) | CYP2C9SLC22A6SLC22A8SLC22A12SLC22A11 | |
| SCHEMBL8171100 | 0.80 | TRPV4 (0.52) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL8167475 | 0.79 | TRPV4 (0.47) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| Hydrochloric Acid SCHEMBL29162081 | 0.78 | TRPV4 (0.50) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL28224487 | 0.78 | TRPV4 (0.46) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL24497681 | 0.76 | TRPV4 (0.52) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL2216854 | 0.76 | TRPV4 (0.52) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL11900937 | 0.76 | TRPV4 (0.52) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL31148778 | 0.76 | TRPV4 (0.52) | TRPV4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL14185017 | 0.76 | KCNQ3 (0.39) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | MERCK SHARP & DOHME CORP. | 2008-05-29 | — | — | US | disclosed |
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | MERCK SHARP & DOHME CORP. | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | AR, CYP17A1, SHBG | TRPV4 3773/4885CYP2C9 2669/4885SLC22A6 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.