Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702799 | 0.81 | CTSA (0.31) | CTSAACHE | |
| SCHEMBL26316292 | 0.81 | HMGCR (0.36) | CTSAACHE | |
| SCHEMBL733409 | 0.80 | ALDH1A1 (0.43) | TSHRCYP3A4 | |
| SCHEMBL18776479 | 0.80 | HMGCR (0.43) | CTSAACHECYP3A4 | |
| SCHEMBL3902813 | 0.79 | CTSA (0.41) | CTSAACHE | |
| SCHEMBL11907935 | 0.77 | CYP3A4 (0.34) | TSHRCYP3A4 | |
| SCHEMBL25192455 | 0.76 | — | — | |
| SCHEMBL17943797 | 0.75 | CYP3A4 (0.48) | ACHETSHRCYP3A4 | |
| SCHEMBL15977306 | 0.75 | TSHR (0.56) | ACHETSHRCYP3A4 | |
| SCHEMBL7006853 | 0.75 | TSHR (0.56) | ACHETSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315227-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2015-11-05 | — | — | US | disclosed |
| US-7368550-B2 | Of given structure; deprotecting using solution containing nucleophile, hydrogen peroxide and performic acid; does not require strong bases | AGILENT TECHNOLOGIES, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070099859-A1 | Phosphorus protecting groups | AGILENT TECHNOLOGIES, INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315227-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | CTSA 670/4885ACHE 2591/4885TSHR 3949/4885 |
| US-20070099859-A1 | Phosphorus protecting groups | ALPP, PSPH, PNKP | CTSA 247/4885ACHE 658/4885TSHR 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.