Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RRM2 | P31350 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573444 | 0.85 | KDM4E (0.55) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL20840585 | 0.83 | MEN1 (0.58) | MEN1KMT2AKDM4EPOLBBRD4 | |
| SCHEMBL16676649 | 0.83 | POLB (0.45) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL15650965 | 0.83 | MAP2K3 (0.50) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL1894761 | 0.81 | L3MBTL1 (0.58) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL18428309 | 0.80 | P2RX7 (0.51) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL20840514 | 0.79 | GLO1 (0.55) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28361358 | 0.76 | METAP1 (0.47) | KDM4EPOLBBRD4ATMTDP1 | |
| SCHEMBL6449076 | 0.76 | RRM2 (0.44) | MEN1KMT2AKDM4EPOLBBRD4 | |
| SCHEMBL13211408 | 0.74 | METAP1 (0.64) | MEN1KMT2APOLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375119-B2 | Amide type carboxamide derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| US-7375119-B2 | Amide type carboxamide derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| EP-1816136-A1 | GPR7-SELECTIVE LIGAND AND USE THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |