Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420993 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL20638633 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HTTSMN1; SMN2TSHRGAA | |
| SCHEMBL23113116 | 0.77 | NOTUM (0.51) | ALDH1A1NPC1 | |
| SCHEMBL4914150 | 0.75 | HTT (0.59) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL21305748 | 0.74 | NOTUM (0.60) | ALDH1A1HTTSMN1; SMN2GAAMEN1 | |
| SCHEMBL6951825 | 0.72 | KDM4E (0.42) | ALDH1A1HTTSMN1; SMN2HSD17B10GAA | |
| SCHEMBL19260255 | 0.72 | HTT (0.74) | ALDH1A1HTTSMN1; SMN2TSHRGAA | |
| SCHEMBL691094 | 0.71 | SIGMAR1 (0.43) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL15389746 | 0.71 | HTT (0.42) | ALDH1A1HTTSMN1; SMN2TSHRGAA | |
| SCHEMBL31662849 | 0.70 | RIPK1 (0.44) | ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239131-A1 | NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2017-11-01 | — | — | EP | disclosed |
| EP-2297088-A2 | NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2011-03-23 | — | — | EP | disclosed |
| EP-2145873-A1 | New compounds with activity that protects against the action of toxins and viruses in intracellular action mode | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-20 | — | — | EP | disclosed |
| WO-2009153457-A2 | NOVEL COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-12-23 | — | — | WO | disclosed |