Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.45 |
| ▸ | THRA | P10827 | 6/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192309 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BPTGESALOX5 | |
| SCHEMBL14192317 | 0.80 | THRB (0.45) | THRBTHRAITGB3ITGA2BMEN1 | |
| SCHEMBL19854961 | 0.79 | THRB (0.48) | THRBTHRAMEN1KMT2AFAAH | |
| SCHEMBL19855810 | 0.78 | THRB (0.47) | THRBTHRAMEN1KMT2AFAAH | |
| SCHEMBL19855815 | 0.76 | LSS (0.37) | THRB | |
| SCHEMBL2567584 | 0.75 | THRB (0.42) | THRBHPGD | |
| SCHEMBL2567585 | 0.75 | THRB (0.42) | THRBHPGD | |
| SCHEMBL19854539 | 0.75 | CNR2 (0.38) | — | |
| SCHEMBL2567988 | 0.74 | THRB (0.41) | THRBHPGD | |
| SCHEMBL2567989 | 0.74 | THRB (0.41) | THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |