SCHEMBL19854539

SCHEMBL19854539

C=CC(=O)NCCCc1ccc(OC(F)(F)C2CCC(CCCCC)CC2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 10/20 0.38
▸ ZDHHC20 Q5W0Z9 1/20 0.37
▸ ZDHHC2 Q9UIJ5 1/20 0.37
▸ CNR1 P21554 6/20 0.35
▸ GAA P10253 1/20 0.35
▸ UBE2M P61081 1/20 0.34
▸ DCUN1D1 Q96GG9 1/20 0.34
▸ SCN9A Q15858 1/20 0.33
▸ TGM2 P21980 1/20 0.32
▸ MTNR1B P49286 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854400 0.85 CCR2 (0.35) CNR2ZDHHC20ZDHHC2CNR1GAA
SCHEMBL19855815 0.85 LSS (0.37) CNR2CNR1
SCHEMBL20370485 0.81 ALOX5 (0.35) CNR2ZDHHC20ZDHHC2CNR1SCN9A
SCHEMBL19856042 0.80 ZDHHC20 (0.39) CNR2ZDHHC20ZDHHC2CNR1GAA
SCHEMBL19855136 0.80 DGAT1 (0.40) CNR2ZDHHC20ZDHHC2GAA
SCHEMBL19722317 0.78 CNR2 (0.35) CNR2CNR1SCN9A
SCHEMBL19722490 0.76 CNR2 (0.34) CNR2CNR1
SCHEMBL14192307 0.75 THRB (0.45) —
SCHEMBL19854392 0.75 RARB (0.41) ZDHHC20ZDHHC2GAASCN9ATGM2
SCHEMBL19856034 0.74 ZDHHC20 (0.41) CNR2ZDHHC20ZDHHC2CNR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 CNR2 1030/4885ZDHHC20 946/4885ZDHHC2 1841/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 CNR2 1030/4885ZDHHC20 946/4885ZDHHC2 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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