Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192558 | 0.91 | KMT2A (0.44) | SRD5A1SRD5A2KMT2AMAPTNPC1 | |
| SCHEMBL14192588 | 0.90 | NPC1 (0.38) | SRD5A1SRD5A2KMT2AMAPTNPC1 | |
| SCHEMBL14192490 | 0.89 | LMNA (0.49) | KMT2AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL14192599 | 0.87 | MAPT (0.35) | SRD5A1SRD5A2KMT2AMAPTNPC1 | |
| SCHEMBL14192562 | 0.87 | NPC1 (0.47) | KMT2AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL14088430 | 0.83 | THRB (0.43) | KMT2AMAPTNPC1RAB9ALMNA | |
| SCHEMBL14192491 | 0.83 | ACACB (0.45) | KMT2AMAPTNPC1LMNAMAOB | |
| SCHEMBL14192561 | 0.81 | NPC1 (0.48) | KMT2AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL14192537 | 0.81 | KMT2A (0.41) | SRD5A1SRD5A2KMT2AMAPTLMNA | |
| SCHEMBL14192538 | 0.81 | NPC1 (0.41) | KMT2AMAPTNPC1LMNACCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |