Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192586 | 0.87 | PTPN11 (0.44) | KMT2ALMNATHRBMAPTALDH1A1 | |
| SCHEMBL21266383 | 0.81 | MAPT (0.39) | KMT2ALMNATHRBMAPTSMN1; SMN2 | |
| SCHEMBL14192517 | 0.81 | SRD5A1 (0.43) | KMT2ALMNAMAOBCCNCCDK8 | |
| SCHEMBL14588245 | 0.80 | KMT2A (0.48) | KMT2ALMNACCNCCDK8THRB | |
| SCHEMBL23082521 | 0.79 | THRB (0.35) | KMT2ATHRBMAPTKDM4EALDH1A1 | |
| SCHEMBL21266163 | 0.77 | MAPT (0.39) | KMT2ALMNATHRBMAPTSMN1; SMN2 | |
| SCHEMBL21266315 | 0.76 | PPARD (0.40) | KMT2ALMNATHRBMAPTALDH1A1 | |
| SCHEMBL13806838 | 0.75 | ADRB2 (0.44) | KMT2ALMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL22099354 | 0.75 | THRB (0.36) | KMT2ATHRBMAPT | |
| SCHEMBL23082414 | 0.75 | THRB (0.39) | KMT2ALMNATHRBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |