Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.76 |
| ▸ | THRA | P10827 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609976 | 0.96 | THRB (0.84) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL13906786 | 0.95 | THRB (0.82) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL3613955 | 0.92 | THRB (0.82) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL1401854 | 0.91 | THRB (0.91) | THRBTHRAKMT2AMEN1RARB | |
| SCHEMBL5665942 | 0.90 | THRB (0.58) | THRBTHRAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7951967 | 0.90 | THRB (0.58) | THRBTHRAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7210214 | 0.90 | THRB (0.58) | THRBTHRAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL778221 | 0.90 | THRB (0.58) | THRBTHRAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14010357 | 0.89 | THRB (0.61) | THRBTHRAKMT2AMEN1MAPT | |
| SCHEMBL14373507 | 0.89 | THRB (0.72) | THRBTHRAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7738346-B2 | Polarizing diffraction element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20060239171-A1 | Polarizing diffraction element and optical head device | ASAHI GLASS COMPANY LIMITED (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1698917-A1 | POLARIZING DIFFRACTION ELEMENT AND OPTICAL HEAD DEVICE | Asahi Glass Company, Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-6562259-B1 | Photopolymerizable liquid crystal monomer is a 4-(4-(alkyloxycarbonyloxy)benzoyloxy)phenyl acrylate; optical head employing the optical element as a polarizing hologram element | ASAHI GLASS COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |