Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192403 | 0.92 | THRB (0.44) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192321 | 0.89 | THRB (0.47) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192424 | 0.86 | THRB (0.44) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192385 | 0.85 | ELANE (0.44) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192541 | 0.84 | CYP2C9 (0.46) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL3620303 | 0.83 | THRB (0.54) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL3620302 | 0.83 | THRB (0.54) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192581 | 0.82 | THRB (0.38) | THRBKMT2AMEN1MAPTTHRA | |
| SCHEMBL14192432 | 0.82 | THRB (0.44) | THRBKMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL14192531 | 0.82 | THRB (0.37) | THRBKMT2AMEN1MAPTTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |