Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192321 | 0.86 | THRB (0.47) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192519 | 0.85 | ITGB3 (0.38) | THRBTHRAMAPTGAA | |
| SCHEMBL14192403 | 0.83 | THRB (0.44) | THRBTHRAMEN1KMT2AELANE | |
| SCHEMBL14192424 | 0.83 | THRB (0.44) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192580 | 0.83 | CYP2C9 (0.40) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192548 | 0.82 | THRB (0.38) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192581 | 0.80 | THRB (0.38) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192565 | 0.79 | CYP2C9 (0.40) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192324 | 0.78 | ELANE (0.47) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL3620302 | 0.78 | THRB (0.54) | THRBTHRAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |