Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192569 | 0.84 | S1PR1 (0.42) | S1PR1SGPL1THRATHRB | |
| SCHEMBL11207311 | 0.81 | S1PR1 (0.45) | MCHR1S1PR1SGPL1MAPTCYP1A2 | |
| SCHEMBL8763562 | 0.81 | TP53 (0.47) | S1PR1SGPL1 | |
| SCHEMBL11208804 | 0.80 | S1PR1 (0.44) | S1PR1SGPL1MAPTSMN1; SMN2THRA | |
| SCHEMBL11209631 | 0.80 | S1PR1 (0.44) | S1PR1SGPL1MAPTSMN1; SMN2THRB | |
| SCHEMBL14192555 | 0.80 | NPC1 (0.43) | MCHR1MAPTCYP1A2NPC1LMNA | |
| SCHEMBL14192561 | 0.79 | NPC1 (0.48) | MAPTCYP1A2NPC1LMNACYP3A4 | |
| SCHEMBL11208842 | 0.78 | S1PR1 (0.43) | S1PR1SGPL1MAPTCYP1A2NPC1 | |
| SCHEMBL14192506 | 0.78 | MCHR1 (0.46) | MCHR1S1PR1SGPL1CYP3A4CYP2D6 | |
| SCHEMBL11210804 | 0.78 | S1PR1 (0.44) | S1PR1SGPL1CYP1A2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |