Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192553 | 0.84 | MCHR1 (0.44) | S1PR1SGPL1THRATHRB | |
| SCHEMBL14192507 | 0.81 | CYP3A4 (0.46) | S1PR1SGPL1THRATHRBCNR2 | |
| SCHEMBL14219185 | 0.78 | CYP1A2 (0.39) | — | |
| SCHEMBL14192543 | 0.78 | TAOK3 (0.42) | THRATHRBCNR2 | |
| SCHEMBL8763749 | 0.76 | S1PR1 (0.52) | S1PR1SGPL1 | |
| SCHEMBL11210393 | 0.75 | S1PR1 (0.47) | S1PR1SGPL1 | |
| SCHEMBL14192567 | 0.74 | RARB (0.51) | THRATHRB | |
| SCHEMBL11208842 | 0.72 | S1PR1 (0.43) | S1PR1SGPL1 | |
| SCHEMBL11210804 | 0.72 | S1PR1 (0.44) | S1PR1SGPL1 | |
| SCHEMBL14192583 | 0.70 | RARB (0.45) | THRATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |