Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192431 | 0.90 | PRSS1 (0.45) | THRBKMT2AMAPTPRSS1TMPRSS2 | |
| SCHEMBL14192546 | 0.87 | MAPT (0.48) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL14192596 | 0.84 | MAPT (0.44) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL17754319 | 0.83 | KMT2A (0.41) | KMT2AMAPTMEN1ALDH1A1PRSS1 | |
| SCHEMBL14192443 | 0.82 | TMPRSS15 (0.40) | THRBKMT2AMAPTMEN1TDP1 | |
| SCHEMBL12242718 | 0.81 | THRB (0.40) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9906563 | 0.80 | THRB (0.41) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL12733745 | 0.79 | KMT2A (0.42) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL17364494 | 0.77 | KMT2A (0.52) | KMT2AMAPTPRSS1TMPRSS2KLK1 | |
| SCHEMBL16920540 | 0.76 | F2 (0.48) | KMT2AMAPTALDH1A1PRSS1TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |