Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12242718 | 0.99 | THRB (0.40) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12733745 | 0.99 | KMT2A (0.42) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL18589712 | 0.92 | KMT2A (0.52) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12242722 | 0.92 | KMT2A (0.47) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12723891 | 0.91 | MAPT (0.40) | THRBMAPTALDH1A1TP53F2 | |
| SCHEMBL10308958 | 0.91 | KMT2A (0.46) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12154254 | 0.90 | KMT2A (0.48) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12242685 | 0.90 | MAPT (0.39) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12242725 | 0.90 | TDP1 (0.40) | THRBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL12225734 | 0.89 | ADRB2 (0.41) | THRBMAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9158053-B2 | Polymerizable liquid crystal compounds, liquid crystal composition comprising the compounds, and optically anisotropic body comprising the composition | LG CHEM, LTD. (KR) | 2015-10-13 | — | — | US | disclosed |
| US-9158053-B2 | Polymerizable liquid crystal compounds, liquid crystal composition comprising the compounds, and optically anisotropic body comprising the composition | LG CHEM, LTD. (KR) | 2015-10-13 | — | — | US | disclosed |
| US-9127104-B2 | Polymerizable liquid crystal compound, a liquid crystal composition comprising the compound, and an optically anisotropic body | LG CHEM, LTD. (KR) | 2015-09-08 | — | — | US | disclosed |
| US-20150099820-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, A LIQUID CRYSTAL COMPOSITION COMPRISING THE COMPOUND, AND AN OPTICALLY ANISOTROPIC BODY | LG ELECTRONICS INC. (KR) | 2015-04-09 | — | — | US | disclosed |
| US-20140034883-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL COMPOSITION COMPRISING THE COMPOUNDS, AND OPTICALLY ANISOTROPIC BODY COMPRISING THE COMPOSITION | LG CHEM, LTD. (KR) | 2014-02-06 | — | — | US | disclosed |
| US-8197710-B2 | Polymerizable compound and polymerizable composition | ADEKA CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| US-7931825-B2 | Polymerizable composition | ADEKA CORPORATION (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20100294990-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100090163-A1 | POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100294990-A1 | POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION | PYM1, SCO2, ZYX | THRB 1211/4885MAPT 2010/4885KMT2A 1150/4885 |
| US-20150099820-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, A LIQUID CRYSTAL COMPOSITION COMPRISING THE COMPOUND, AND AN OPTICALLY ANISOTROPIC BODY | RCC1, NLK, MAP1LC3C | THRB 4881/4885MAPT 12/4885KMT2A 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.