Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 5/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192570 | 0.91 | CYP2C9 (0.39) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192580 | 0.89 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14219188 | 0.83 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192531 | 0.79 | THRB (0.37) | MAPTRAB9AMEN1KMT2ATHRA | |
| SCHEMBL14192450 | 0.79 | RAB9A (0.47) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192406 | 0.78 | TP53 (0.47) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192446 | 0.78 | TP53 (0.47) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14010374 | 0.77 | RAB9A (0.45) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192552 | 0.77 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL14192449 | 0.77 | CYP2C9 (0.55) | CYP2C9ALDH1A1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |